Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 20nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 22nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
Affinity DataIC50: 23nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 25nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 28nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 52nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 70nMAssay Description:Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 80nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 95nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 99nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 120nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 130nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 140nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 190nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 290nMAssay Description:Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 330nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 350nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 360nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 400nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 400nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 430nMAssay Description:Inhibition of VEGFR2 in HUE cells assessed as inhibition of VEGF-induced autophosphorylation treated for 90 mins before VEGF challenge by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 530nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 600nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 630nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 670nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 750nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 750nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 840nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1 [99-307](Homo sapiens (Human))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 850nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Marthasterias glacialis (starfish))
Technische Universitat Braunschweig
Technische Universitat Braunschweig
Affinity DataIC50: 850nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of VEGFR2 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase PLK1(Homo sapiens (Human))
Technische Universitat Braunschweig
Curated by ChEMBL
Technische Universitat Braunschweig
Curated by ChEMBL
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PLK1 assessed as [33Pi] incorporation by microplate scintillation counting in presence of 1 uM ATPMore data for this Ligand-Target Pair